ABSTRACT
A endocardite trombótica não bacteriana é caracterizada pela deposição de trombos e fibrina sobre valvas cardíacas normais ou degeneradas na ausência de germes. A patologia está relacionada a estados inflamatórios crônicos, com maior incidência de fenômenos embólicos quando comparada à endocardite infecciosa. Os autores relatam o caso de um paciente masculino, 63 anos, com adenocarcinoma de sítio primário oculto e embolia sistêmica.
Nonbacterial thrombotic endocarditis (NBTE) is a disease characterized by deposition of thrombi and fibrin on normal or degenerated cardiac valves in the absence of microorganisms. This condition is more commonly seen in chronic inflammatory states, and is associated with higher incidence of thromboembolic events than infective endocarditis. We report the case of a 63-year old male patient with adenocarcinoma of unknown primary site and systemic embolism.
La endocarditis trombótica no bacteriana se caracteriza por el depósito de trombos de fibrina en las válvulas cardíacas normales o degenerados en ausencia de gérmenes. La patología se relaciona con estados inflamatorios crónicos, con una mayor incidencia de fenómenos embólicos cuando comparada a endocarditis infecciosa. Los autores refieren el caso de un paciente varón, de 63 años con adenocarcinoma de sitio primario desconocido y la embolia sistémica.
Subject(s)
Humans , Male , Middle Aged , Adenocarcinoma/complications , Endocarditis/etiology , Liver Neoplasms/complications , Neoplasms, Unknown Primary/complications , Thromboembolism/etiology , Fatal Outcome , Heart Valve Diseases/etiologyABSTRACT
O carcinoma neuroendócrino de pequenas células usualmente tem como sítio primário o pulmão e a sua origem na bexiga é rara. O diagnóstico dos tumores localizados na bexiga é realizado pela biópsia através da cistoscopia ou biópsia transuretral, com posterior análise histológica e imunohistoquímica. O prognóstico é sombrio, com sobrevida média de 8% em 5 anos. O objetivo do presente trabalho é relatar um caso de carcinoma de pequenas células com sítio primário na bexiga em paciente do sexo feminino
The small cell neuroendocrine carcinoma usually has as a primary site the lung, and its origin in the bladder is rare. The diagnosis of tumors in bladder is made through biopsy by cystoscopy or transurethral biopsy with subsequent histological and immunohistochemical analyses. The prognosis is bleak, with mean survival of 8% in 5 years. Here we report a case of small cell carcinoma with primary site in the bladder in a female patient
Subject(s)
Humans , Male , Female , Carcinoma, Small Cell/diagnosis , Carcinoma, Small Cell/pathologyABSTRACT
The combination of neutropenia and fever, with or without documented infection, is a commun complication in cancer patients receiving chemotherapy. The prompt institution of empirical broad-spectrum antibiotic therapy for febrile neutropenic patients has been shown to reduce the rate of early death and morbidity in cancer populations undergoing chemotherapy. Three different regimens for considerations as initial empiric therapy are presented. Alternatives such as outpatient regimens to low risk patients and monotherapy are discussed. If confirmed prospectively, the results presented here may enable clinicians to identify low risk groups and treat neutropenia and fever with good results and better economic and psychological cost.